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Cryptococcus neoformans (Sanfelice) Vuillemin
Cryptococcus neoformans (Sanfelice) Vuillemin
規(guī)格:
貨期:
編號(hào):B239352
品牌:Mingzhoubio

標(biāo)準(zhǔn)菌株
定量菌液
DNA
RNA

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產(chǎn)品名稱 Cryptococcus neoformans (Sanfelice) Vuillemin
商品貨號(hào) B239352
Strain Designations 52 [52D, CDC B3179]
Alternate State Filobasidiella neoformans Kwon-Chung
Application
Biomedical Research and Development Material
Emerging infectious disease research
Biosafety Level 2

Biosafety classification is based on U.S. Public Health Service Guidelines, it is the responsibility of the customer to ensure that their facilities comply with biosafety regulations for their own country.
Product Format freeze-dried
Storage Conditions Frozen: -80°C or colder
Freeze-Dried: 2°C to 8°C
Live Culture: See Propagation Section
Type Strain no
Antigenic Properties serotype D
Preceptrol® no
Comments
Phenotypic switching
Antibody response to capsular glucuronoxylomannan, GXM, in mice
Experimental infection in rats
Facultative intracellular pathogen
Crystal formation
Immunoglobulin M specificity to epitopes
Induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta in human microglia
Interaction between lung surfactants and alveolar macrophages in defense against Cryptococcus neoformans
Melanization decreases the suseptibility of Cryptococcus neoformans to enzymatic degradation.
Multilocus enzyme typing
Medium ATCC® Medium 200: YM agar or YM broth
ATCC® Medium 28: Emmons' modification of Sabouraud's agar
ATCC® Medium 336: Potato dextrose agar (PDA)
Growth Conditions
Temperature: 37°C
Atmosphere: Typical aerobic
Sequenced Data
18S ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and 26S ribosomal RNA gene, partial sequence

GGTTTCCGTAGGTGAACCTGCGGAAGGATCAGTAGAGAATATTGGACTTTGGTCCATTTATCTACCCATCTACACCTGTGAACTGTTTATGTGCTTCGGCACGTTTTACACAAACTTCTAAATGTAATGAATGTAATCATATTATAACAATAATAAAACTTTCAACAACGGATCTCTTGGCTTCCACATCGATGAAGAACGCAGCGAAATGCGATAAGTAATGTGAATTGCAGAATTCAGTGAATCATCGAGTCTTTGAACGCAACTTGCGCCCTTTGGTATTCCGAAGGGCATGCCTGTTTGAGAGTCATGAAAATCTCAATCCCTCGGGTTTTATTACCTGTTGGACTTGGATTTGGGTGTTTGCCGCGACCTGCAAAGGACGTCGGCTCGCCTTAAATGTGTTAGTGGGAAGGTGATTACCTGTCAGCCCGGCGTAATAAGTTTCGCTGGGCCTATGGGGTAGTCTTCGGCTTGCTGATAACAACCATCTCTTTTTGTTTGACCTCAAATCAGGTAGGGCTACCCGCTGAACTTAAGCATATCAATAA


D1D2 region of the 26S ribosomal RNA gene

ATATCAATAAGCGGAGGAAAAGAAACTAACAAGGATTCCCTTAGTAACGGCGAGTGAACCGGGAAGAGCTCAAATTTGAAATCTGGCGTCCTCCGGGCGTCCGAGTTGTAATCTACAGAAACGTTTTCCGTGCTGGACCGTGTCTAAGTCCCTTGGAATAGGGTATCAAAGAGGGTGACAATCCCGTACTTGACACGATCACCAGTGCTCTGTGATACGTTTTCTACGAGTCGCGTTACTTGGGAGTGTAGCGCAAAATGGGTGGTAAACTCCATCTAAAGCTAAATATTGGTGGAAGACCGATAGCGAACAAGTACCGTGAGGGAAAGATGAAAAGCACTTTGGAAAGAGAGTTAAACAGTACGTGAAATTGTTGAAAGGGAAACGATTGAAGTCAGTCGTGTCTATTGGGTTCAGCCAGTTCTGCTGGTGTATTCCCTTTAGACGGGTCAACATCAGTTCTGATCGGTGGATAAGGGCTGGAGGAATGTGGCACTCTTCGGGGTGTGTTATAGCCTCCTGTCGCATACACTGGTTGGGACTGAGGAATGCAGCTCGCCTTTATGGCCGGGGTTCGCCCACGTTCGAGCTTAGGATGTTGACAAAATGGCTTTAAACGAC
Name of Depositor JE Bennett
Isolation
Human cerebrospinal fluid, Maryland, USA
Cross References

Nucleotide (GenBank) : L05428 17S rRNA gene, complete gene

Nucleotide (GenBank) : L14068 5.8S and 25S ribosomal RNA sequences

Nucleotide (GenBank) : L27078 5S ribosomal RNA and intergenic spacer

Nucleotide (GenBank) : AF032431 orotate phosphoribosyltransferase (URA5) gene, complete coding sequence

References

Wilson DE, et al. Serologic grouping of Cryptococcus neoformans. Proc. Soc. Exp. Biol. Med. 127: 820-823, 1968. PubMed: 5651140

Fan M, et al. The 5S rRNA and the rRNA intergenic spacer of the two varieties of Cryptococcus neoformans. J. Med. Vet. Mycol. 33: 215-221, 1995. PubMed: 8531018

Brandt ME, et al. Multilocus enzyme typing of Cryptococcus neoformans. J. Clin. Microbiol. 31: 2819-2823, 1993. PubMed: 8253996

Gyetko MR, et al. Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans. J. Clin. Invest. 97: 1818-1826, 1996. PubMed: 8621764

Mukherjee S, et al. J774 murine macrophage-like cell interactions with Cryptococcus neoformans in the presence and absence of opsonins. J. Infect. Dis. 173: 1222-1231, 1996. PubMed: 8627076

Wang Y, et al. Melanin, melanin "ghosts," and melanin composition in Cryptococcus neoformans. Infect. Immun. 64: 2420-2424, 1996. PubMed: 8698461

Gross NT, et al. In vitro effect of lung surfactant on alveolar macrophage defence mechanisms against Cryptococcus neoformans. Mycopathologia 144: 21-27, 1999. PubMed: 10422270

Nussbaum G, et al. Molecular and idiotypic analyses of the antibody response to Cryptococcus neoformans glucuronoxylomannan-protein conjugate vaccine in autoimmune and nonautoimmune mice. Infect. Immun. 67: 4469-4476, 1999. PubMed: 10456888

Fries BC, et al. Phenotypic switching in Cryptococcus neoformans results in changes in cellular morphology and glucuronoxylomannan structure. Infect. Immun. 67: 6076-6083, 1999. PubMed: 10531269

Goldman DL, et al. Persistent Cryptococcus neoformans pulmonary infection in the rat is associated with intracellular parasitism, decreased inducible nitric oxide synthase expression, and altered antibody responsiveness to cryptococcal polysaccharide. Infect. Immun. 68: 832-838, 2000. PubMed: 10639453

Feldmesser M, et al. Cryptococcus neoformans is a facultative intracellular pathogen in murine pulmonary infection. Infect. Immun. 68: 4225-4237, 2000. PubMed: 10858240

Feldmesser M, et al. Intracellular crystal formation as a mechanism of cytotoxicity in murine pulmonary Cryptococcus neoformans infection. Infect. Immun. 69: 2723-2727, 2001. PubMed: 11254641

Nakouzi A, et al. Molecular basis for immunoglobulin M specificity to epitopes in Cryptococcus neoformans polysaccharide that elicit protective and nonprotective antibodies. Infect. Immun. 69: 3398-3409, 2001. PubMed: 11292763

Goldman D, et al. Cryptococcus neoformans induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta in human microglia: role of specific antibody and soluble capsular polysaccharide. Infect. Immun. 69: 1808-1815, 2001. PubMed: 11179358

Olszewski MA, et al. Regulatory effects of macrophage inflammatory protein 1alpha/CCL3 on the development of immunity to Cryptococcus neoformans depend on expression of early inflammatory cytokines. Infect. Immun. 69: 6256-6263, 2001. PubMed: 11553568

Beenhouwer DO, et al. Both Th1 and Th2 cytokines affect the ability of monoclonal antibodies to protect mice against Cryptococcus neoformans. Infect. Immun. 69: 6445-6455, 2001. PubMed: 11553589

Rosas AL, Casadevall A. Melanization decreases the suseptibility of Cryptococcus neoformans to enzymatic degradation. Mycopathologia 151: 53-56, 2001.

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